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2025 JACC: Basic to Translational Science - ARTICLE

News: August 18, 2025

Heart failure with preserved ejection fraction (HFpEF) accounts for ∼50% of HF cases. The ZSF1-obese rat model recapitulates clinical features of HFpEF including hypertension, obesity, metabolic syndrome, exercise intolerance, and diastolic dysfunction. We utilized a systems-biology approach to...

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Welcome, Dr. Ching-Cheng Hsu

News: June 30, 2025

Welcome our new lab member, Dr. Ching-Cheng Hsu, who received his Ph.D. from National Cheng Kung University, Taiwan, and joins the Nguyen Lab in Jun. He is interested in mammalian regenerative transcriptome and proteome.

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Dr. Kunhua Song's Lab Group

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Sean Christiansen

Person: Research Scientist

I am a research scientist under the tutelage of Dr. Song and I conduct translational research within the field of cardiology. I developed a research background in cancer immunology during my undergraduate career, which has lent itself well to understanding the signaling mechanisms for...

Effects of prolonged ethanol vapor exposure on forced swim behavior, and neuropeptide Y and corticotropin-releasing factor levels in rat brains.

Publication: Journal Article

Walker, Brendan M, David A Drimmer, Jennifer L Walker, Tianmin Liu, Aleksander A Mathé, and Cindy L Ehlers. 2010. “Effects of Prolonged Ethanol Vapor Exposure on Forced Swim Behavior, and Neuropeptide Y and Corticotropin-Releasing Factor Levels in Rat Brains.”. Alcohol (Fayetteville, N.Y.) 44 (6): 487-93.

The alpha1 adrenergic receptor antagonist prazosin reduces heroin self-administration in rats with extended access to heroin administration.

Publication: Journal Article

Greenwell, Thomas N, Brendan M Walker, Pietro Cottone, Eric P Zorrilla, and George F Koob. 2009. “The Alpha1 Adrenergic Receptor Antagonist Prazosin Reduces Heroin Self-Administration in Rats With Extended Access to Heroin Administration.”. Pharmacology, Biochemistry, and Behavior 91 (3): 295-302.

Increased alcohol drinking in isolate-housed alcohol-preferring rats.

Publication: Journal Article

Ehlers, Cindy L, Brendan M Walker, Jerry P Pian, Jennifer L Roth, and Craig J Slawecki. 2007. “Increased Alcohol Drinking in Isolate-Housed Alcohol-Preferring Rats.”. Behavioral Neuroscience 121 (1): 111-9.

Mitochondrial H2S Regulates BCAA Catabolism in Heart Failure.

Publication: Journal Article

Li, Zhen, Huijing Xia, Thomas E Sharp, Kyle B LaPenna, John W Elrod, Kevin M Casin, Ken Liu, et al. 2022. “Mitochondrial H2S Regulates BCAA Catabolism in Heart Failure.”. Circulation Research 131 (3): 222-35.