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Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence.

Publication: Journal Article

Walker, Brendan M, and George F Koob. 2008. “Pharmacological Evidence for a Motivational Role of Kappa-Opioid Systems in Ethanol Dependence.”. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 33 (3): 643-52.

Intra-ventral tegmental area heroin-induced place preferences in rats are potentiated by peripherally administered alprazolam.

Publication: Journal Article

Walker, Brendan M, and Aaron Ettenberg. 2005. “Intra-Ventral Tegmental Area Heroin-Induced Place Preferences in Rats Are Potentiated by Peripherally Administered Alprazolam.”. Pharmacology, Biochemistry, and Behavior 82 (3): 470-7.

The effects of alprazolam on conditioned place preferences produced by intravenous heroin.

Publication: Journal Article

Walker, Brendan M, and Aaron Ettenberg. 2003. “The Effects of Alprazolam on Conditioned Place Preferences Produced by Intravenous Heroin.”. Pharmacology, Biochemistry, and Behavior 75 (1): 75-80.

Outstanding Research Achievement Award - USF

News: September 16, 2024

From advancing our understanding of hurricanes to improving public transit systems, to pursuing new treatments for addiction, Alzheimer’s disease, cancer, diabetes, and cardiovascular and infectious diseases, 27 USF faculty members are being recognized on Tuesday, September 17 with Outstanding...

Alexander Baron

Person: Medical student, RISE 2022

Amy Pham

Person:

Open positions

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Things are constantly evolving, best to contact Dr Walker for up-to-date availability. Training Opportunities Research within the LAAN allows for multidisciplinary interactions among post-doctoral, graduate and undergraduate trainees. Within the LAAN, the necessary theoretical and practical...

Targeting dysregulated kappa-opioid receptors reduces working memory deficits in alcohol use disorder

News: March 08, 2022

A USF Health preclinical study suggests that kappa-opioid antagonists offer a potential treatment to help alcohol-dependent patients cut back or quit drinking. For the full article click here

Understanding Alcohol dependence

News: December 16, 2019

Brendan Walker, PhD, is a USF Health Morsani College of Medicine professor in psychiatry and behavioral neurosciences. He discusses his research on how the development of alcohol dependence (and potentially other addictions) induces depression and dysphoria leading to even more alcohol use to self...

PhD, Brendan Walker

Person: Principal Investigator

My long-term research interest has been the neurobiology of motivational systems and how acute and long-term alcohol (and other drugs of abuse such as heroin) impact neural systems to promote increased drug seeking and consumption. Utilizing a combination of behavioral, anatomical, pharmacological...