Breslin Lab
Our laboratory investigates problems pertaining to microvascular dysfunction and lymphatic disease.
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55 results found
Sigma-1 receptor activation-induced glycolytic ATP production and endothelial barrier enhancement.
Motawe, Zeinab Y, Forouzandeh Farsaei, Salma S Abdelmaboud, Javier Cuevas, and Jerome W Breslin. 2020. “Sigma-1 Receptor Activation-Induced Glycolytic ATP Production and Endothelial Barrier Enhancement.”. Microcirculation (New York, N.Y. : 1994) 27 (6): e12620.
Evidence of functional ryanodine receptors in rat mesenteric collecting lymphatic vessels.
Jo, Michiko, Andrea N Trujillo, Ying Yang, and Jerome W Breslin. 2019. “Evidence of Functional Ryanodine Receptors in Rat Mesenteric Collecting Lymphatic Vessels.”. American Journal of Physiology. Heart and Circulatory Physiology 317 (3): H561-H574.
Sphingosine-1-phosphate protects against brain microvascular endothelial junctional protein disorganization and barrier dysfunction caused by alcohol.
Alves, Natascha G, Sarah Y Yuan, and Jerome W Breslin. 2019. “Sphingosine-1-Phosphate Protects Against Brain Microvascular Endothelial Junctional Protein Disorganization and Barrier Dysfunction Caused by Alcohol.”. Microcirculation (New York, N.Y. : 1994) 26 (1): e12506.
Research on excessively “leaky” microvessels may lead to better trauma treatment
From Blood Vessels to Lymphatics and Back Again.
Murfee, Walter L, and Jerome W Breslin. 2025. “From Blood Vessels to Lymphatics and Back Again.”. Function (Oxford, England).
Apolipoprotein M (ApoM) Ameliorates Acute Alcohol Intoxication (AAI)-Hemorrhagic Shock and Resuscitation (HSR)-Induced Microvascular Leakage.
Chang, Mengmeng, and Jerome W Breslin. 2025. “Apolipoprotein M (ApoM) Ameliorates Acute Alcohol Intoxication (AAI)-Hemorrhagic Shock and Resuscitation (HSR)-Induced Microvascular Leakage.”. Microcirculation (New York, N.Y. : 1994) 32 (7): e70030.
Guidelines for Evaluating Endothelial Function in Vascular Tissue.
McCarthy, Cameron G, Christian Aalkjær, Pooneh Bagher, Andreas M Beyer, Ebbe Boedtkjer, Gisele F Bomfim, Jerome W Breslin, et al. 2026. “Guidelines for Evaluating Endothelial Function in Vascular Tissue.”. American Journal of Physiology. Heart and Circulatory Physiology.
Evaluation of Glycolysis and Mitochondrial Function in Endothelial Cells Using the Seahorse Analyzer.
Motawe, Zeinab Y, Salma S Abdelmaboud, and Jerome W Breslin. 2024. “Evaluation of Glycolysis and Mitochondrial Function in Endothelial Cells Using the Seahorse Analyzer.”. Methods in Molecular Biology (Clifton, N.J.) 2711: 241-56.
Endothelial mechanisms for inactivation of inflammation-induced hyperpermeability.
Nepali, Prerna R, Pía C Burboa, Mauricio A Lillo, Patricio E Mujica, Toru Iwahashi, Jihang Zhang, Ricardo G Durán, et al. 2023. “Endothelial Mechanisms for Inactivation of Inflammation-Induced Hyperpermeability.”. American Journal of Physiology. Heart and Circulatory Physiology 324 (5): H610-H623.