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Treatment with shCCL20-CCR6 nanodendriplexes and human mesenchymal stem cell therapy improves pathology in mice with repeated traumatic brain injury
Markoutsa, E., K. Mayilsamy, D. Gulick, S. S. Mohapatra, and S. Mohapatra. 2022. Treatment With ShCCL20-CCR6 Nanodendriplexes and Human Mesenchymal Stem Cell Therapy Improves Pathology in Mice With Repeated Traumatic Brain Injury.
DnaJs are enriched in tau regulators.
Esquivel, Abigail R, Shannon E Hill, and Laura J Blair. 2023. “DnaJs Are Enriched in Tau Regulators.”. International Journal of Biological Macromolecules 253 (Pt 7): 127486.
Genetically engineered mouse models of FK506-binding protein 5.
Gebru, Niat T, Shannon E Hill, and Laura J Blair. 2023. “Genetically Engineered Mouse Models of FK506-Binding Protein 5.”. Journal of Cellular Biochemistry.
Small molecule targeting long noncoding RNA GAS5 administered intranasally improves neuronal insulin signaling and decreases neuroinflammation in an aged mouse model.
Patel, Rekha S, Ashley Lui, Charles Hudson, Lauren Moss, Robert P Sparks, Shannon E Hill, Yan Shi, et al. 2023. “Small Molecule Targeting Long Noncoding RNA GAS5 Administered Intranasally Improves Neuronal Insulin Signaling and Decreases Neuroinflammation in an Aged Mouse Model.”. Scientific Reports 13 (1): 317.
Chaperoning activity of the cyclophilin family prevents tau aggregation.
Hill, Shannon E, Abigail R Esquivel, Santiago Rodriguez Ospina, Lauren M Rahal, Chad A Dickey, and Laura J Blair. 2022. “Chaperoning Activity of the Cyclophilin Family Prevents Tau Aggregation.”. Protein Science : A Publication of the Protein Society 31 (11): e4448.
Evidence against a contribution of the CCAAT-enhancer binding protein homologous protein (CHOP) in mediating neurotoxicity in rTg4510 mice.
Criado-Marrero, Marangelie, Danielle M Blazier, Lauren A Gould, Niat T Gebru, Santiago Rodriguez Ospina, Debra S Armendariz, April L Darling, David Beaulieu-Abdelahad, and Laura J Blair. 2022. “Evidence Against a Contribution of the CCAAT-Enhancer Binding Protein Homologous Protein (CHOP) in Mediating Neurotoxicity in RTg4510 Mice.”. Scientific Reports 12 (1): 7372.
Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology.
Sandusky-Beltran, Leslie A, Andrii Kovalenko, Devon S Placides, Kevin Ratnasamy, Chao Ma, Jerry B Hunt, Huimin Liang, et al. 2021. “Aberrant AZIN2 and Polyamine Metabolism Precipitates Tau Neuropathology.”. The Journal of Clinical Investigation 131 (4).
Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war.
Favretto, Filippo, David Flores, Jeremy D Baker, Timo Strohäker, Loren B Andreas, Laura J Blair, Stefan Becker, and Markus Zweckstetter. 2020. “Catalysis of Proline Isomerization and Molecular Chaperone Activity in a Tug-of-War.”. Nature Communications 11 (1): 6046.
Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease.
Webster, Jack M, April L Darling, Vladimir N Uversky, and Laura J Blair. 2019. “Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease.”. Frontiers in Pharmacology 10: 1047.