Cellular reprogramming of fibroblasts in heart regeneration.
Chi, Congwu, and Kunhua Song. 2023. “Cellular Reprogramming of Fibroblasts in Heart Regeneration.”. Journal of Molecular and Cellular Cardiology 180: 84-93.
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Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Enables Modeling of Human Hypertrophic Cardiomyopathy.
Knight, Walter E, Yingqiong Cao, Ying-Hsi Lin, Congwu Chi, Betty Bai, Genevieve C Sparagna, Yuanbiao Zhao, et al. 2021. “Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Enables Modeling of Human Hypertrophic Cardiomyopathy.”. Stem Cell Reports 16 (3): 519-33.
Cardiac Regeneration: New Insights Into the Frontier of Ischemic Heart Failure Therapy.
Riching, Andrew S, and Kunhua Song. 2020. “Cardiac Regeneration: New Insights Into the Frontier of Ischemic Heart Failure Therapy.”. Frontiers in Bioengineering and Biotechnology 8: 637538.
Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis.
Riching, Andrew S, Etienne Danis, Yuanbiao Zhao, Yingqiong Cao, Congwu Chi, Rushita A Bagchi, Brianna J Klein, et al. 2021. “Suppression of Canonical TGF-β Signaling Enables GATA4 to Interact With H3K27me3 Demethylase JMJD3 to Promote Cardiomyogenesis.”. Journal of Molecular and Cellular Cardiology 153: 44-59.
Danon Disease-Associated LAMP-2 Deficiency Drives Metabolic Signature Indicative of Mitochondrial Aging and Fibrosis in Cardiac Tissue and hiPSC-Derived Cardiomyocytes.
Del Favero, Giorgia, Alois Bonifacio, Teisha J Rowland, Shanshan Gao, Kunhua Song, Valter Sergo, Eric D Adler, Luisa Mestroni, Orfeo Sbaizero, and Matthew R G Taylor. 2020. “Danon Disease-Associated LAMP-2 Deficiency Drives Metabolic Signature Indicative of Mitochondrial Aging and Fibrosis in Cardiac Tissue and HiPSC-Derived Cardiomyocytes.”. Journal of Clinical Medicine 9 (8).
Deubiquitylase USP9X maintains centriolar satellite integrity by stabilizing pericentriolar material 1 protein.
Han, Ke-Jun, Zhiping Wu, Chad G Pearson, Junmin Peng, Kunhua Song, and Chang-Wei Liu. 2019. “Deubiquitylase USP9X Maintains Centriolar Satellite Integrity by Stabilizing Pericentriolar Material 1 Protein.”. Journal of Cell Science 132 (2).
Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes.
Riching, Andrew S, Yuanbiao Zhao, Yingqiong Cao, Pilar Londono, Hongyan Xu, and Kunhua Song. 2018. “Suppression of Pro-Fibrotic Signaling Potentiates Factor-Mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes.”. Journal of Visualized Experiments : JoVE, no. 136.
ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression.
Zhou, Huanyu, Maria Gabriela Morales, Hisayuki Hashimoto, Matthew E Dickson, Kunhua Song, Wenduo Ye, Min S Kim, et al. 2017. “ZNF281 Enhances Cardiac Reprogramming by Modulating Cardiac and Inflammatory Gene Expression.”. Genes & Development 31 (17): 1770-83.
High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling.
Zhao, Yuanbiao, Pilar Londono, Yingqiong Cao, Emily J Sharpe, Catherine Proenza, Rebecca O’Rourke, Kenneth L Jones, et al. 2015. “High-Efficiency Reprogramming of Fibroblasts into Cardiomyocytes Requires Suppression of Pro-Fibrotic Signalling.”. Nature Communications 6: 8243.
Novel Gottingen miniswine model of heart failure with preserved ejection fraction integrating multiple comorbidities
Sharp, TE., A. Scarborough, Z. Li, DJ. Polhemus, H. Hidalgo, JD. Schumacher, TR. Matsuura, et al. 2022. “Novel Gottingen Miniswine Model of Heart Failure With Preserved Ejection Fraction Integrating Multiple Comorbidities”. JACC: Basic to Translational Science.