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Leptin-enhanced neointimal hyperplasia is reduced by mTOR and PI3K inhibitors.
Shan, Jian, Thomas B Nguyen, Hana Totary-Jain, Hayes Dansky, Steven O Marx, and Andrew R Marks. 2008. “Leptin-Enhanced Neointimal Hyperplasia Is Reduced by MTOR and PI3K Inhibitors.”. Proceedings of the National Academy of Sciences of the United States of America 105 (48): 19006-11.
Rapamycin resistance is linked to defective regulation of Skp2.
Totary-Jain, Hana, Despina Sanoudou, Cula N Dautriche, Hillary Schneller, Lester Zambrana, and Andrew R Marks. 2012. “Rapamycin Resistance Is Linked to Defective Regulation of Skp2.”. Cancer Research 72 (7): 1836-43.
Tailoring mTOR-based therapy: molecular evidence and clinical challenges.
Santulli, Gaetano, and Hana Totary-Jain. 2013. “Tailoring MTOR-Based Therapy: Molecular Evidence and Clinical Challenges.”. Pharmacogenomics 14 (12): 1517-26.
A selective microRNA-based strategy inhibits restenosis while preserving endothelial function.
Santulli, Gaetano, Anetta Wronska, Kunihiro Uryu, Thomas G Diacovo, Melanie Gao, Steven O Marx, Jan Kitajewski, et al. 2014. “A Selective MicroRNA-Based Strategy Inhibits Restenosis While Preserving Endothelial Function.”. The Journal of Clinical Investigation 124 (9): 4102-14.
Decreased LIN28B in preeclampsia impairs human trophoblast differentiation and migration.
Canfield, John, Sefa Arlier, Ezinne F Mong, John Lockhart, Jeffrey VanWye, Ozlem Guzeloglu-Kayisli, Frederick Schatz, et al. 2019. “Decreased LIN28B in Preeclampsia Impairs Human Trophoblast Differentiation and Migration.”. FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology 33 (2): 2759-69.
Anti-atherosclerotic therapies: Milestones, challenges, and emerging innovations.
Hetherington, Isabella, and Hana Totary-Jain. 2022. “Anti-Atherosclerotic Therapies: Milestones, Challenges, and Emerging Innovations.”. Molecular Therapy : The Journal of the American Society of Gene Therapy 30 (10): 3106-17.
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What is the placenta and how does it protect the fetus?
Our lab has exceptional global impact with cases such as the Arabic BBC News reaching out to our PI for an interview looking to explore how the placenta acts as a protective barrier against viral infection, and learn about the many biological functions it performs to ensure healthy growth and...