The exceptionally high reactivity of Cys 621 is critical for electrophilic activation of the sensory nerve ion channel TRPA1
Bahia, P. K., T. A. Parks, K. R. Stanford, and D. A. 2016. “The Exceptionally High Reactivity of Cys 621 Is Critical for Electrophilic Activation of the Sensory Nerve Ion Channel TRPA1”. J Gen Physiol 147: 451-65.