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2025 JACC: Basic to Translational Science - ARTICLE

Heart failure with preserved ejection fraction (HFpEF) accounts for ∼50% of HF cases. The ZSF1-obese rat model recapitulates clinical features of HFpEF including hypertension, obesity, metabolic syndrome, exercise intolerance, and diastolic dysfunction. We utilized a systems-biology approach to...

Sean Christiansen

I am a research scientist under the tutelage of Dr. Song and I conduct translational research within the field of cardiology. I developed a research background in cancer immunology during my undergraduate career, which has lent itself well to understanding the signaling mechanisms for...