Cardiometabolic Heart Failure and HFpEF: Still Chasing Unicorns.
Sharp, Thomas E, David J Lefer, and Steven R Houser. 2019. “Cardiometabolic Heart Failure and HFpEF: Still Chasing Unicorns.”. JACC. Basic to Translational Science 4 (3): 422-24.
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Adjunctive therapy with an oral H2S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction.
Doiron, Jake E, Huijing Xia, Xiaoman Yu, Alexandra R Nevins, Kyle B LaPenna, Thomas E Sharp, Traci T Goodchild, et al. 2024. “Adjunctive Therapy With an Oral H2S Donor Provides Additional Therapeutic Benefit Beyond SGLT2 Inhibition in Cardiometabolic Heart Failure With Preserved Ejection Fraction.”. British Journal of Pharmacology 181 (21): 4294-4310.
Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.
Whitehead, Anna K, Nicholas D Fried, Zhen Li, Kandasamy Neelamegam, Charlotte S Pearson, Kyle B LaPenna, Thomas E Sharp, et al. 2022. “Alpha7 Nicotinic Acetylcholine Receptor Mediates Chronic Nicotine Inhalation-Induced Cardiopulmonary Dysfunction.”. Clinical Science (London, England : 1979) 136 (12): 973-87.
Reduced Hydrogen Sulfide Bioavailability Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction.
Doiron, Jake E, Mahmoud H Elbatreek, Huijing Xia, Xiaoman Yu, W H Wilson Tang, Kyle B LaPenna, Thomas E Sharp, et al. 2024. “Reduced Hydrogen Sulfide Bioavailability Contributes to Cardiometabolic Heart Failure With Preserved Ejection Fraction.”. BioRxiv : The Preprint Server for Biology.
Efficacy of a Novel Mitochondrial-Derived Peptide in a Porcine Model of Myocardial Ischemia/Reperfusion Injury.
Sharp, Thomas E, Zhenwei Gong, Amy Scarborough, Eric S Goetzman, Murtuza J Ali, Pablo Spaletra, David J Lefer, Radhika H Muzumdar, and Traci T Goodchild. 2020. “Efficacy of a Novel Mitochondrial-Derived Peptide in a Porcine Model of Myocardial Ischemia/Reperfusion Injury.”. JACC. Basic to Translational Science 5 (7): 699-714.
Renal Denervation Prevents Heart Failure Progression Via Inhibition of the Renin-Angiotensin System.
Sharp, Thomas E, David J Polhemus, Zhen Li, Pablo Spaletra, Stephen Jenkins, John P Reilly, Christopher J White, Daniel R Kapusta, David J Lefer, and Traci T Goodchild. 2018. “Renal Denervation Prevents Heart Failure Progression Via Inhibition of the Renin-Angiotensin System.”. Journal of the American College of Cardiology 72 (21): 2609-21.
Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model.
Toib, Amir, Chen Zhang, Giulia Borghetti, Xiaoxiao Zhang, Markus Wallner, Yijun Yang, Constantine D Troupes, et al. 2017. “Remodeling of Repolarization and Arrhythmia Susceptibility in a Myosin-Binding Protein C Knockout Mouse Model.”. American Journal of Physiology. Heart and Circulatory Physiology 313 (3): H620-H630.
Hydrogen Sulfide Attenuates Renin Angiotensin and Aldosterone Pathological Signaling to Preserve Kidney Function and Improve Exercise Tolerance in Heart Failure.
Li, Zhen, Chelsea L Organ, Jianming Kang, David J Polhemus, Rishi K Trivedi, Thomas E Sharp, Jack S Jenkins, Ya-Xiong Tao, Ming Xian, and David J Lefer. 2018. “Hydrogen Sulfide Attenuates Renin Angiotensin and Aldosterone Pathological Signaling to Preserve Kidney Function and Improve Exercise Tolerance in Heart Failure.”. JACC. Basic to Translational Science 3 (6): 796-809.
Protein Kinase C Inhibition With Ruboxistaurin Increases Contractility and Reduces Heart Size in a Swine Model of Heart Failure With Reduced Ejection Fraction.
Sharp, Thomas E, Hajime Kubo, Remus M Berretta, Timothy Starosta, Markus Wallner, Giana J Schena, Alexander R Hobby, et al. 2017. “Protein Kinase C Inhibition With Ruboxistaurin Increases Contractility and Reduces Heart Size in a Swine Model of Heart Failure With Reduced Ejection Fraction.”. JACC. Basic to Translational Science 2 (6): 669-83.
Acute right heart failure after hemorrhagic shock and trauma pneumonectomy-a management approach: A blinded randomized controlled animal trial using inhaled nitric oxide.
Lubitz, Andrea L, Lars O Sjoholm, Amy Goldberg, Abhijit Pathak, Thomas Santora, Thomas E Sharp, Markus Wallner, et al. 2017. “Acute Right Heart Failure After Hemorrhagic Shock and Trauma Pneumonectomy-a Management Approach: A Blinded Randomized Controlled Animal Trial Using Inhaled Nitric Oxide.”. The Journal of Trauma and Acute Care Surgery 82 (2): 243-51.