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Ultrasound Renal Denervation Attenuates Early Cardiac Remodeling After Acute Myocardial Infarction in a Swine Model of Hypertensions and Dyslipidemia: A Pilot Study Acute myocardial infarction (AMI) patients typically present with a constellation of one or more risk factors including hypertension...

Heart failure with preserved ejection fraction (HFpEF) accounts for ∼50% of HF cases. The ZSF1-obese rat model recapitulates clinical features of HFpEF including hypertension, obesity, metabolic syndrome, exercise intolerance, and diastolic dysfunction. We utilized a systems-biology approach to...

Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF Heart failure with preserved ejection fraction (HFpEF) presents significant treatment challenges. We assessed hydrogen sulfide (H 2S) bioavailability in HFpEF patients and 2 animal models: the "2-hit" L-NAME + high-fat...