About
Center for Regenerative Medicine - CRM
A University Laboratory
Our lab is interested in the molecular mechanisms that regulate cardiac and skeletal muscle development and how they are disrupted in human cardiovascular diseases. Over the past ten years, we have focused on the role of non-coding RNAs, including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), in the regulation of gene expression.
Dr. Wang is also the inaugural director of the newly created Center for Regenerative Medicine here at USF Health. Future studies will include cutting edge new studies in the mechanisms regulating cell and tissue renewal and investigations into approaches to leverage these findings for disease therapies.
Research
Research Area
Molecular Mechanisms
Dr. D Wang's laboratory focuses on the molecular mechanisms of cardiac, smooth and skeletal muscle development and diseases. They revealed that myocardin is essential for cardiovascular development. Over the past decade, the Wang lab studies non-coding RNAs, in particular microRNAs (miRNAs) and they have demonstrated that miRNAs play a critical role in controlling cardiac and skeletal muscle proliferation and differentiation. Their lab also studies the function and molecular mechanisms of long non-coding RNAs (lncRNAs) in the heart and cardiovascular disease. Dr. D Wang has made substantial contribution to our understanding of the molecular mechanisms underlying heart development and disease.
Dr. D Wang's discovery of myocardin represents a landmark which has opened an entire new area in the cardiovascular biology and has now become the focus of intense investigation by many laboratories around the world.
Research Area
more info to come
Describe an area of your research.
