Welcome, Anh Lam
Nguyen Lab
Research area
Nguyen Lab uncovers the gene-level mechanisms that control heart and limb muscle regeneration, enabling new therapeutic strategies for currently irreversible striated muscle injuries.
We are broadly interested in discovering the master gene-regulated mechanism of striated muscle regeneration in injury
Love heart
Disassemble heart
Meet the Principal Investigator
Lastest discovery
Dr. Nguyen is the first to uncover the full story of the Meis1-Hoxb13 pathway, including drug discovery for heart regeneration, in the Nature journal.
1. Nguyen NUN et al. A Calcineurin-Hoxb13 Axis Regulates The Growth Mode of Mammalian Cardiomyocytes. Nature 582, 271–276 (2020).
2. Lam NT*, Nguyen NUN*, et al. Targeting calcineurin induces cardiomyocyte proliferation in adult mice. Nat Cardiovasc Res 1, 679–688 (2022). *Contributed equally. (accompanied by an Editorial: Watanabe, H., Sucov, H.M. Cardiomyocyte proliferation by calcineurin inhibition.)
3. Ahmed MS*, Nguyen NUN*, et al. Identification of FDA-Approved Drugs That Induce Heart Regeneration in Mammals. Nat Cardiovasc Res 3, 372–388 (2024). *Contributed equally. (accompanied by an Editorial: Yuan, X., Braun, T. Toward drug-induced heart regeneration.)
