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High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling.

Publication: Journal Article

Zhao, Yuanbiao, Pilar Londono, Yingqiong Cao, Emily J Sharpe, Catherine Proenza, Rebecca O’Rourke, Kenneth L Jones, et al. 2015. “High-Efficiency Reprogramming of Fibroblasts into Cardiomyocytes Requires Suppression of Pro-Fibrotic Signalling.”. Nature Communications 6: 8243.

Truman Roland

Person: PhD student

I am a graduate student pursuing a PhD in medical sciences at the Morsani College of Medicine (MCOM)). I earned my B.S. in biomedical engineering from USF in 2023 where I specialized in tissue engineering and wound healing. Now, I apply these tissue engineering techniques to the regeneration of the...

Innovation

News: September 20, 2024

The USF TTO filed a patent application for Dr. Chi and Dr. Conniff's innovative discoveries. Congratulations, Congwu and Amanda!

USF secured $738 million in research funding for 2024

News: December 10, 2024

USF achieved a record-breaking $738 million in 2024 research funding, bringing the university closer to reaching its goal of $1 billion in annual research funding. https://www.usf.edu/news/2024/usf-sets-new-record-with-738-million-in-research-funding.aspx

Cell differentiation modifies the p53 transcriptional program through a combination of gene silencing and constitutive transactivation.

Publication: Journal Article

Tatavosian, Roubina, Micah G Donovan, Matthew D Galbraith, Huy N Duc, Maria M Szwarc, Molishree U Joshi, Amy Frieman, et al. 2023. “Cell Differentiation Modifies the P53 Transcriptional Program through a Combination of Gene Silencing and Constitutive Transactivation.”. Cell Death and Differentiation 30 (4): 952-65.

Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart.

Publication: Journal Article

Zhao, Yuanbiao, Andrew S Riching, Walter E Knight, Congwu Chi, Lindsey J Broadwell, Yanmei Du, Mostafa Abdel-Hafiz, et al. 2022. “Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart.”. Circulation 146 (9): 699-714.

Lysosomal Abnormalities in Cardiovascular Disease.

Publication: Journal Article

Chi, Congwu, Andrew S Riching, and Kunhua Song. 2020. “Lysosomal Abnormalities in Cardiovascular Disease.”. International Journal of Molecular Sciences 21 (3).

Angiotensin II Induces Skeletal Muscle Atrophy by Activating TFEB-Mediated MuRF1 Expression.

Publication: Journal Article

Bois, Philipp Du, Cristina Pablo Tortola, Doerte Lodka, Melanie Kny, Franziska Schmidt, Kunhua Song, Sibylle Schmidt, Rhonda Bassel-Duby, Eric N Olson, and Jens Fielitz. 2015. “Angiotensin II Induces Skeletal Muscle Atrophy by Activating TFEB-Mediated MuRF1 Expression.”. Circulation Research 117 (5): 424-36.

Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor.

Publication: Journal Article

Long, Chengzu, Chad E Grueter, Kunhua Song, Song Qin, Xiaoxia Qi, Megan Kong, John M Shelton, et al. 2014. “Ataxia and Purkinje Cell Degeneration in Mice Lacking the CAMTA1 Transcription Factor.”. Proceedings of the National Academy of Sciences of the United States of America 111 (31): 11521-6.

Heart repair by cardiac reprogramming.

Publication: Journal Article

Nam, Young-Jae, Kunhua Song, and Eric N Olson. 2013. “Heart Repair by Cardiac Reprogramming.”. Nature Medicine 19 (4): 413-5.