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Validation of transcatheter left ventricular electromechanical mapping for assessment of cardiac function and targeted transendocardial injection in a porcine ischemia-reperfusion model.

Publication: Journal Article

Taghavi, Sharven, Jason M Duran, Remus M Berretta, Catherine A Makarewich, Foram Udeshi, Thomas E Sharp, Hajime Kubo, Steven R Houser, and Jon C George. 2012. “Validation of Transcatheter Left Ventricular Electromechanical Mapping for Assessment of Cardiac Function and Targeted Transendocardial Injection in a Porcine Ischemia-Reperfusion Model.”. American Journal of Translational Research 4 (2): 240-6.

2026 Dr. Sharp Speaks at Emory University

News: February 02, 2026

Dr. Sharp speaks at Emory University, Cardiovascular Biology Seminar Series. Talk entitled Microbiota and Metabolites as Mediators: Uncovering the Cardiovascular Consequences of Alcohol-induced Gut Dysbiosis.

Adjunctive Therapy with an Oral H2S Donor Provides Additional Therapeutic Benefit Beyond SGLT2 Inhibition in Cardiometabolic HFpEF

Publication: Journal Article

Doiron, JE., H. Xio, X. Yu, AR. Nevins, KB. LaPenna, TE. Sharp, TT. Goodchild, et al. 2024. “Adjunctive Therapy With an Oral H2S Donor Provides Additional Therapeutic Benefit Beyond SGLT2 Inhibition in Cardiometabolic HFpEF”. British Journal of Pharmacology.

Early Renal Denervation Attenuates Cardiorenal Dysfunction in Heart Failure with Preserved Ejection Fraction

Publication: Journal Article

Doiron, JE., Z. Li, TE. Sharp, KB. LaPenna, K. Koul, AJ. Malek, SJ. Shah, et al. 2024. “Early Renal Denervation Attenuates Cardiorenal Dysfunction in Heart Failure With Preserved Ejection Fraction”. Journal of the American Heart Association.

Mitochondrial H2S Regulates BCAA Catabolism in Heart Failure

Publication: Journal Article

Li, Z., H. Xia, TE. Sharp, KB. LaPenna, JW. Elrod, JW. Calvert, FN. Salloumn, et al. 2022. “Mitochondrial H2S Regulates BCAA Catabolism in Heart Failure”. Circulation Research.

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2024 CARDIOVASCULAR RESEARCH FOUNDATION TCT Conference

News: October 28, 2024

Abstract Presented: "Ultrasound Renal Denervation Protects the Ischemic-Reperfused Myocardium in a swine Model of Hypertension and Dyslipidemia"

2025 AHA BCVS - CONFERENCE: Dr. Sharp speaks on Renal Denervation to Treat Heart Failure

News: July 23, 2025

Dr. Sharp speaks at the 2025 American Heart Association, Basic Cardiovascular Sciences Scientific Session, Baltimore, MD. AHA BCVS is one of the largest meetings globally dedicated to fundamental and translational research in cardiovascular science. The BCVS Scientific Sessions is a unique and...

2025 Circulation Research - ARTICLE

News: September 17, 2025

Background: Recent studies suggest aberrant elevation of iNOS (inducible NO synthase) expression and excessive protein s-nitrosylation promote the pathogenesis of heart failure with preserved ejection fraction (HFpEF). However, the interplay between NO bioavailability, enzymatic regulation of...

Common Heart Failure With Preserved Ejection Fraction Animal Models Yield Disparate Myofibril Mechanics.

Publication: Journal Article

Fenwick, Axel J, Vivek P Jani, Brian Foster, Thomas E Sharp, Traci T Goodchild, Kyle LaPenna, Jake E Doiron, et al. 2024. “Common Heart Failure With Preserved Ejection Fraction Animal Models Yield Disparate Myofibril Mechanics.”. Journal of the American Heart Association 13 (2): e032037.