The Appalachian Mind Health Initiative (AMHI) Study
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AMHI, a clinical research study funded by The Patient-Centered Outcomes Research Institute (PCORI), focuses on evaluating electronic Cognitive Behavioral Therapy (eCBT)—an online talk therapy—as a viable treatment for adults dealing with major depression. This approach proves particularly advantageous for those in rural communities, where mental health resources are scarce. eCBT stands out for its affordability, accessibility (available for at-home use), range of treatment options, and effectiveness, prompting its widespread integration into health plans nationwide. Despite its growing popularity, questions remain about its effectiveness and which individuals benefit most. At our Healthy Minds Lab, we strive to fill these gaps with evidence. By examining the intersections between antidepressants and the benefits of guided versus unguided eCBT or online cognitive behavioral therapy, we aim to empower patients and clinicians alike to make informed treatment decisions for those that battle with depression.
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If you have any questions or would like further information about the AMHI study, please do not hesitate to visit the study website at https://www.amhi-home.org/. To reach out to us call 813-974-1575 or send us an email at AppMindHealth@usf.edu.
Optimizing Digital Behavioral Treatment for Co-occurring Insomnia and Depression (DoD- funded Study)
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Directed by Dr. Wilfred Pigeon at the University of Rochester and funded by the Department of Defense, this study focuses on identifying the most effective digital behavioral treatment for veterans facing both insomnia and depression. The research tackles two primary objectives aimed at addressing critical gaps in clinical practice and research. Firstly, it examines whether treating insomnia and depression sequentially yields better outcomes compared to single treatments, determining the optimal treatment sequence if so. Secondly, the study investigates heterogeneity of treatment effects (HTE), seeking to personalize treatment approaches based on individual patient needs.
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Under the guidance of Dr. Bossarte, the Healthy Minds Lab plays a crucial role in the study. The lab supports recruitment efforts through outreach and technical assistance, manages the blinded randomization process, designs and administers study assessments, oversees participant interaction with SilverCloud interventions, and develops final study instruments.
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For more information or any inquiries about the DoD study, please contact us via phone at 813-974-4300 or email at MCOM-SleepStudy@usf.edu. We are here to assist you!