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Advances in the Generation of Constructed Cardiac Tissue Derived from Induced Pluripotent Stem Cells for Disease Modeling and Therapeutic Discovery.

Publication: Journal Article

Roland, Truman J, and Kunhua Song. 2024. “Advances in the Generation of Constructed Cardiac Tissue Derived from Induced Pluripotent Stem Cells for Disease Modeling and Therapeutic Discovery.”. Cells 13 (3).

Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling.

Publication: Journal Article

Chi, Congwu, Walter E Knight, Andrew S Riching, Zhen Zhang, Roubina Tatavosian, Yonghua Zhuang, Radu Moldovan, et al. 2023. “Interferon Hyperactivity Impairs Cardiogenesis in Down Syndrome via Downregulation of Canonical Wnt Signaling.”. IScience 26 (7): 107012.

Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model.

Publication: Journal Article

Waugh, Katherine A, Ross Minter, Jessica Baxter, Congwu Chi, Matthew D Galbraith, Kathryn D Tuttle, Neetha P Eduthan, et al. 2023. “Triplication of the Interferon Receptor Locus Contributes to Hallmarks of Down Syndrome in a Mouse Model.”. Nature Genetics 55 (6): 1034-47.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Publication: Journal Article

Klionsky, Daniel J, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, et al. 2021. “Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th Edition)1.”. Autophagy 17 (1): 1-382.

Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation.

Publication: Journal Article

Stratton, Matthew S, Rushita A Bagchi, Marina B Felisbino, Rachel A Hirsch, Harrison E Smith, Andrew S Riching, Blake Y Enyart, et al. 2019. “Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation.”. Circulation Research 125 (7): 662-77.

LAMP-2B regulates human cardiomyocyte function by mediating autophagosome-lysosome fusion.

Publication: Journal Article

Chi, Congwu, Andrea Leonard, Walter E Knight, Kevin M Beussman, Yuanbiao Zhao, Yingqiong Cao, Pilar Londono, et al. 2019. “LAMP-2B Regulates Human Cardiomyocyte Function by Mediating Autophagosome-Lysosome Fusion.”. Proceedings of the National Academy of Sciences of the United States of America 116 (2): 556-65.

HDAC11 suppresses the thermogenic program of adipose tissue via BRD2.

Publication: Journal Article

Bagchi, Rushita A, Bradley S Ferguson, Matthew S Stratton, Tianjing Hu, Maria A Cavasin, Lei Sun, Ying-Hsi Lin, et al. 2018. “HDAC11 Suppresses the Thermogenic Program of Adipose Tissue via BRD2.”. JCI Insight 3 (15).

Heart repair by reprogramming non-myocytes with cardiac transcription factors.

Publication: Journal Article

Song, Kunhua, Young-Jae Nam, Xiang Luo, Xiaoxia Qi, Wei Tan, Guo N Huang, Asha Acharya, et al. 2012. “Heart Repair by Reprogramming Non-Myocytes With Cardiac Transcription Factors.”. Nature 485 (7400): 599-604.

Zhen Zhang

Person: Lab Manager

I have been the lab manager since 2021. I earned my master’s degree in Law from Shanghai University in China. I have over 15 years of experience in customer service and education. My primary focus is laboratory management and logistics. Additionally, I culture and differentiate human iPSCs and...

Amanda Sales Conniff

Person: Postdoctoral Fellow

As a postdoctoral researcher, I am immersed in cardiovascular research, utilizing advanced techniques to explore the intricate aspects of heart development and disease. Our lab uniquely combines human induced pluripotent stem cell-based platforms (hiPSC) with mouse models of cardiovascular disease...