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Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition

Publication: Journal Article

“Hypothalamic Steroid Receptor Coactivator-2 Regulates Adaptations to Fasting and Overnutrition”. 2021. Cell Reports.

Melanocortin 4 receptor is not required for estrogenic regulations on energy homeostasis and reproduction

Publication: Journal Article

“Melanocortin 4 Receptor Is Not Required for Estrogenic Regulations on Energy Homeostasis and Reproduction”. 2017. Metabolism.

Asprosin is a centrally-acting orexigenic hormone

Publication: Journal Article

“Asprosin Is a Centrally-Acting Orexigenic Hormone”. 2017. Nature Medicine.

A small potassium current in AgRP/NPY neurons regulates feeding behavior and energy metabolism

Publication: Journal Article

“A Small Potassium Current in AgRP/NPY Neurons Regulates Feeding Behavior and Energy Metabolism”. 2016. Cell Reports.

Chunling Chen, PhD

Person: Postdoctoral Scholar

I earned my bachelor’s degree at Huazhong University of Science and Technology and then completed my PhD in Toxicology at the University of Iowa, where I studied neuronal mechanisms underlying neurodevelopmental disorders. I continued this research as a postdoctoral trainee at the University of Iowa...

Martina Boaglio

Person: Undergraduate Student

I am a senior majoring in Cellular and Molecular Biology at the University of South Florida, where I’ve developed a strong foundation in molecular techniques and bacterial genetics. My research experience spans of hands-on work in molecular biology, exploring gene expression and protein function. I...

Dr. Kristine McDermott Recognized for Excellence at ObesityWeek 2025

News: November 07, 2025

Dr. Kristine McDermott represented the Xu Laboratory at The Obesity Society’s ObesityWeek 2025 conference, held November 4–7 in Atlanta, GA. Her research abstract received special recognition from the Neuroscience Section, and she was invited to deliver a blitz talk highlighting her work on...

Chenling Meng, PhD

Person: Advanced Research Scientist

I received my Ph.D. in Biomedical Sciences from the Chinese University of Hong Kong, where my research focused on epigenetic regulation and signal transduction in spermatogenesis and epididymal differentiation. In 2019, I joined MD Anderson Cancer Center as a postdoctoral fellow to study macrophage...

Python metabolomics uncovers a conserved postprandial metabolite and gut–brain feeding pathway

Publication: Journal Article

“Python Metabolomics Uncovers a Conserved Postprandial Metabolite and Gut–brain Feeding Pathway”. 2026. Nature Metabolism.

Center for Molecular Psychiatry

The Center for Molecular Psychiatry at USF Morsani College of Medicine (MCOM) conducts cutting-edge research on brain metabolism, obesity, and psychiatric disorders. Led by Dr. Yong Xu and team members including Lucas Tu, Yongjie Yang, Qingzhuo Liu, Yuxue Yang, Yongxiang Li, Jinjing Jian, Fuhui Wang, Hailan Liu, and others, the center integrates neuroscience, genomics, electrophysiology, and psychiatry to advance mental health