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Cardiovascular dysfunction induced by combined exposure to nicotine inhalation and high fat diet

Publication: Journal Article

Whitehead, A., Z. Li, KB. LaPenna, TE. Sharp, DJ. Lefer, E. Lazartigues, and X. Yue. 2023. “Cardiovascular Dysfunction Induced by Combined Exposure to Nicotine Inhalation and High Fat Diet”. American Journal of Physiology-Heart and Circulatory Physiology.

Alpha7 Nicotinic Acetylcholine Receptor Mediates Chronic Nicotine Inhalation-Induced Cardiopulmonary Dysfunction

Publication: Journal Article

Whitehead, A., N. Fried, Z. Li, K. Neelamegan, C. Pearson, KB. LaPenna, Sharp TE., et al. 2022. “Alpha7 Nicotinic Acetylcholine Receptor Mediates Chronic Nicotine Inhalation-Induced Cardiopulmonary Dysfunction”. Clinical Science.

Novel Gottingen miniswine model of heart failure with preserved ejection fraction integrating multiple comorbidities

Publication: Journal Article

Sharp, TE., A. Scarborough, Z. Li, DJ. Polhemus, H. Hidalgo, JD. Schumacher, TR. Matsuura, et al. 2022. “Novel Gottingen Miniswine Model of Heart Failure With Preserved Ejection Fraction Integrating Multiple Comorbidities”. JACC: Basic to Translational Science.

2024 AMERICAN HEART ASSOCIATION Basic Cardiovascular (BCVS) Scientific Sessions

News: July 22, 2024

Abstract Presented: "Gut Microbial Metabolite Phenylacetylglutamine Leads to Cardiomyocyte Hypercontractility and Vascular Endothelial Cell Activation."

We are located in the USF Health Heart Institute at the University of South Florida, Morsani College of Medicine, Tampa, FL. Our academic affiliation is in the Department of Molecular Pharmacology and Physiology. Our laboratory is focused on discovery-based, hypothesis-driven biomedical research...

Thanh Trung Van

Person: Graduate Student

Thanh Trung Van, B.S., M.S. Trung is a graduate student in the Department of Molecular Pharmacology and Physiology at USF Morsani College of Medicine in Tampa, Florida, USA. Trung received his bachelor degree from the University of Florida where he majored in microbiology and graduated cum laude. He...

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Sharp Lab

Cardiovascular dysfunction induced by combined exposure to nicotine inhalation and high fat diet

Alpha7 Nicotinic Acetylcholine Receptor Mediates Chronic Nicotine Inhalation-Induced Cardiopulmonary Dysfunction

Novel Gottingen miniswine model of heart failure with preserved ejection fraction integrating multiple comorbidities

2024 AMERICAN HEART ASSOCIATION Basic Cardiovascular (BCVS) Scientific Sessions

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Thanh Trung Van

Thromboxane A2 blockade attenuates ethanol-induced myocardial inflammation: Sipping from the same bottle

2025 Inaugural USF Heart Institute Symposium: Dr. Sharp Speaks on Gut-derived metabolites & CVD

Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure.