News + Updates

Dr. Sharp speaks at the 2025 Inaugural USF Heart Institute Symposium. Talk entitled "Microbiota, Metabolites, and Myocardium: Cardiovascular Consequences of Alcohol-Induced Gut Dysbiosis"

Dr. Sharp speaks at the 2025 HFpEF Summit, Beverly Hills, CA. A world-class summit which brings together internationally recognized experts discussing the preclinical and clinical findings in...

Comprehensive Echocardiographic Protocol for Pigs with Emphasis on Diastolic Function: Advantages over MRI Assessment

Swine are increasingly utilized in cardiovascular research due to their...

Alcohol-induced gut microbial reorganization and associated overproduction of phenylacetylglutamine promotes cardiovascular disease

The mechanism(s) underlying gut microbial metabolite (GMM)...

The HFpEF Summit is a bi-annual, two-day meeting which brings together internationally recognized leaders in the areas of clinical, translational and biological studies of heart failure with preserved...

Abstract Presented:

"Ultrasound Renal Denervation Protects the Ischemic-Reperfused Myocardium in a swine Model of Hypertension and Dyslipidemia"

Thromboxane A2 blockade attenuates ethanol-induced myocardial inflammation: Sipping from the same bottle.

Originally, light-to-moderate alcohol consumption was believed to provide some protective...

Abstract Presented:

"Gut Microbial Metabolite Phenylacetylglutamine Leads to Cardiomyocyte Hypercontractility and Vascular Endothelial Cell Activation." 

We are excited to welcome Trung to the Sharp Laboratory as a graduate student! Trung is a native Floridian, who received his undergradute degree from the University of Florida followed by a Master's...

Abstract Presented: 

"Alcohol-induced Gut Dysbiosis Results in Phenylacetylglutamine Accumulation leading to Cardiovascular Dysfunction."