News + Updates

Dr. Sharp speaks at the 2025 HFpEF Summit, Beverly Hills, CA. A world-class summit which brings together internationally recognized experts discussing the preclinical and clinical findings in...

Comprehensive Echocardiographic Protocol for Pigs with Emphasis on Diastolic Function: Advantages over MRI Assessment

Swine are increasingly utilized in cardiovascular research due to their...

Alcohol-induced gut microbial reorganization and associated overproduction of phenylacetylglutamine promotes cardiovascular disease

The mechanism(s) underlying gut microbial metabolite (GMM)...

The HFpEF Summit is a bi-annual, two-day meeting which brings together internationally recognized leaders in the areas of clinical, translational and biological studies of heart failure with preserved...

Abstract Presented:

"Ultrasound Renal Denervation Protects the Ischemic-Reperfused Myocardium in a swine Model of Hypertension and Dyslipidemia"

Thromboxane A2 blockade attenuates ethanol-induced myocardial inflammation: Sipping from the same bottle.

Originally, light-to-moderate alcohol consumption was believed to provide some protective...

Abstract Presented:

"Gut Microbial Metabolite Phenylacetylglutamine Leads to Cardiomyocyte Hypercontractility and Vascular Endothelial Cell Activation." 

We are excited to welcome Trung to the Sharp Laboratory as a graduate student! Trung is a native Floridian, who received his undergradute degree from the University of Florida followed by a Master's...

Abstract Presented: 

"Alcohol-induced Gut Dysbiosis Results in Phenylacetylglutamine Accumulation leading to Cardiovascular Dysfunction." 

The Sharp Laboratory has joined USF, Morsani College of Medicine, Department of Molecular Pharmacology and Physiology. We will reside at the downtown campus - USF MDD. We are also affiliated with the...