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High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling.

Publication: Journal Article

Zhao, Yuanbiao, Pilar Londono, Yingqiong Cao, Emily J Sharpe, Catherine Proenza, Rebecca O’Rourke, Kenneth L Jones, et al. 2015. “High-Efficiency Reprogramming of Fibroblasts into Cardiomyocytes Requires Suppression of Pro-Fibrotic Signalling.”. Nature Communications 6: 8243.

Truman Roland

Person: PhD student

I am a graduate student pursuing a PhD in medical sciences at the Morsani College of Medicine (MCOM)). I earned my B.S. in biomedical engineering from USF in 2023 where I specialized in tissue engineering and wound healing. Now, I apply these tissue engineering techniques to the regeneration of the...

Novel Gottingen miniswine model of heart failure with preserved ejection fraction integrating multiple comorbidities

Publication: Journal Article

Sharp, TE., A. Scarborough, Z. Li, DJ. Polhemus, H. Hidalgo, JD. Schumacher, TR. Matsuura, et al. 2022. “Novel Gottingen Miniswine Model of Heart Failure With Preserved Ejection Fraction Integrating Multiple Comorbidities”. JACC: Basic to Translational Science.

2024 AMERICAN HEART ASSOCIATION Basic Cardiovascular (BCVS) Scientific Sessions

News: July 22, 2024

Abstract Presented: "Gut Microbial Metabolite Phenylacetylglutamine Leads to Cardiomyocyte Hypercontractility and Vascular Endothelial Cell Activation."

Katia Maria Gomes Andrade

Person: Postdoctoral Research Scholar

My name is Katia Andrade, and I am from Brazil. I am a post-doc in Dr. Zhigao Wang’s lab at the USF Heart institute (2023 - present). I have a Ph.D. in Systems Biology from the Institute of Biomedical Sciences at the University of São Paulo (ICB-USP, 2020 - Brazil), with a Sandwich Ph.D. at Harvard...

Erick Fenk

Person:

My name is Erick Fenk, I obtained my B.S. in Biological Science and M.S. in Biomedical Science at Florida Atlantic University, in 2022 and 2023 respectively. Following Shortly after graduation, I joined Dr. Zhigao Wang’s lab as a research technician studying PPP1R3G in mouse models of ischemia...

About

Page

We are located in the USF Health Heart Institute at the University of South Florida, Morsani College of Medicine, Tampa, FL. Our academic affiliation is in the Department of Molecular Pharmacology and Physiology. Our laboratory is focused on discovery-based, hypothesis-driven biomedical research...

Sharp Lab

Totary Jain Lab

Yiwen Zha, MEd

Person: Lab Manager

Ms. Yiwen Zha is a Social and Behavioral Researcher in the Department of Emergency Medicine in the Division of Social Medicine at the Morsani College of Medicine, University of South Florida. She is passionate about using research and data analysis to inform policy decisions and drive change...