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A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites

Publication: Journal Article

“A β-Hydroxybutyrate Shunt Pathway Generates Anti-Obesity Ketone Metabolites”. 2025. Cell.

Lac-Phe induces hypophagia via inhibiting AgRP neurons in mice

Publication: Journal Article

“Lac-Phe Induces Hypophagia via Inhibiting AgRP Neurons in Mice”. 2025. Nature Metabolism.

Translational potential of mouse models of human metabolic disease

Publication: Journal Article

“Translational Potential of Mouse Models of Human Metabolic Disease”. 2024. Cell.

Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia

Publication: Journal Article

“Anoctamin 4 Channel Currents Activate Glucose-Inhibited Neurons in the Mouse Ventromedial Hypothalamus During Hypoglycemia”. 2023. Journal of Clinical Investigation.

AgRP neurons trigger long-term potentiation and facilitate food seeking

Publication: Journal Article

“AgRP Neurons Trigger Long-Term Potentiation and Facilitate Food Seeking”. 2021. Translational Psychiatry.

5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding

Publication: Journal Article

“5-HT Recruits Distinct Neurocircuits to Inhibit Hunger-Driven and Non-Hunger-Driven Feeding”. 2021. Molecular Psychiatry.

Estrogen receptor-α in the medial amygdala prevents stress-induced elevations in blood pressure in females

Publication: Journal Article

“Estrogen Receptor-α in the Medial Amygdala Prevents Stress-Induced Elevations in Blood Pressure in Females”. 2016. Hypertension.

Yong Xu, MD, PhD

Person: Principal Investigator, Professor, Director of Center for Molecular Psychiatry

I received medical training in Tongji Medical University (1994-2002) with a specialty in gastroenterology. I then received PhD training in cell biology and neuroscience, working with Dr. Teresa Krukuff at University of Alberta in Canada (2002-2006) to study the neural mechanisms for blood pressure...

Yongjie Yang, PhD

Person: Assistant Professor

I received my B.S. in 1995 from Huazhong University of Science and Technology in Wuhan, China, and earned my Ph.D. in 2006 from the Shanghai Institute of Biochemistry and Cell Biology. Following this, I moved to Houston, Texas, where I joined Dr. Qiang Tong’s lab at the Children’s Nutrition Research...

Qingzhuo Liu, PhD

Person: Postdoctoral Scholar

I earned my PhD from Fudan University in 2023, where I investigated the dynamics and molecular mechanisms of synaptic transmission and plasticity using ex vivo electrophysiology, molecular and cellular approaches, and advanced fluorescence imaging. I began my postdoctoral training in Dr. Yong Xu’s...