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Ho Lab

Our lab focuses on understanding gut health in relation to nutrition and health condition in preterm infants with an emphasis on anemia and oral iron supplementation. We use in-vitro human enteroid models and patient samples to understand the bacteria-host interactions.

Featured Research Areas

In-vitro Enteroid Models

Gut inflammation, oxidative stress, iron uptake, and intestinal permeability are all examined using fetal enteroids and monolayers grown in the lab.

In-vitro fetal enteroids under a microscope

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Clinical Studies/Patient Samples

Examination of patient samples reveals changes in the microbiome, biomarkers, and other indicators of gut health induced by anemia and iron supplementation.

Diagram of the clinical trials process from treatment to sample analysis

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Predictive Treatment Responses 

Artificial intelligence and machine learning help us generate mechanistic hypotheses and predict patient responses to treatment.

Diagram depicting AI prediction of neonatal pain

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Lighting the way

Forefront of Research

Our lab focuses on understanding infant gut health from a holistic perspective. By combining clinical studies, patient care, artificial intelligence/machine learning, and cell culture/basic science we attempt to discover cause and effect relationships among nutrition, anemia and iron supplementation, intestinal inflammation, and gut microbiota.
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Fluorescent staining of a cauliflower fetal enteroid grayscale image of a cauliflower fetal enteroid

 

Our Team on The Forefront of Research

 

Our team is led by Dr. Tina Ho, who oversees clinical studies, patient care, and translational research. Daily lab functions and in vitro experiments are run by our postdoc, Hannah Wapshott-Stehli, and lab manager, Madison Huszar. The translational research is supported by a group of competent and accomplished undergraduate students who are trained by the lab and, with experience, may pursue their own research projects. The clinical studies are coordinated and executed by a skilled team of medical students at Tampa General Hospital and USF's Morsani College of Medicine. 
Meet Our Team

Our Partners

 

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