Hyperbaric Oxygen Treatment (HBOT) for Veterans & Active Duty Service Members with Traumatic Brain Injuries.
About the project: This randomized clinical trial tests whether HBOT can help reduce symptoms after traumatic brain injury compared to inactive (or placebo) HBOT. We are recruiting U.S. Service Members and Veterans. The total length of time for the study is approximately 4 months. Participants will complete 40 daily HBOT dives and three sets of questionnaires, blood draws, and brain games.
- How it Works:
- Each participant will undergo a total of 40 HBOT dives over 12 weeks. Each dive session takes approximately 90 minutes (~75 minutes in the HBOT chamber).
- The Study Process:
- Participants will be randomized into two groups. Participants do not get to choose their group. One group will get 40 HBOT dives pressurized at 100% oxygen therapy (treatment group). The other group will get 40 HBOT dives at 21% oxygen (inactive HBOT group), which is normal air pressure.
- Throughout the study, participants will be asked to
- Complete questionnaires.
- Complete brain game.
- Give blood samples to test for markers of inflammation.
- Participants may also choose to participate in further testing, which will include:
- Giving a stool sample before and after the 40 dives.
- Receiving electroencephalogram (EEG) and more brain games.
- Accepting and agreeing to wear a device that will monitor sleep patterns.
- Status: Currently recruiting
- Contact & Eligibility:
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For eligibility criteria and more information, please visit: USF Health HBOT in Veterans Clinical Trial
- Location:
- University of South Florida, Health Campus 13220 Laurel Drive Tampa, FL 33612
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